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A guide to AMH

What is AMH and why is it important in fertility treatment and preservation for females?

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What is AMH?

AMH stands for Anti-Mullerian Hormone. AMH is produced directly by the ovarian follicles and therefore AMH levels correlate with the number of antral follicles in the ovaries.

It has been documented that women with lower AMH have lower antral follicular counts and therefore produce a lower number of eggs compared with women with higher levels.

Most fertility specialists now use AMH routinely in fertility assessment to assess the ovarian function and to predict the remaining reproductive lifespan. It can be assessed on any day of your period and it does not vary with the menstrual cycle. It cannot predict outcome of treatment.

It is important to understand that AMH will naturally decline with age. Occasionally, high levels can be suggestive of Polycystic Ovarian Syndrome in some patients.

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AMH and antral follicle count

Antral follicles are normally between 2 and 8 millimetres in size when viewed during an ultrasound scan. The numbers of these follicles is related to the cohort of all follicles within the ovary.

An AMH level is the test of choice for measuring ovarian reserve. It can be measured on any day of the cycle and does not vary from cycle to cycle. This is why most infertility specialists today use AMH to check ovarian reserve, rather than the old FSH level.

The AMH blood test combined with an antral follicle count is a powerful tool for the assessment of reproductive potential.

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AMH and ageing

Fertility declines with age and it is not possible to predict the rate of decline for an individual woman.

Some women may wrongly assume that if they are having regular periods, that their fertility is fine. However, this is not always the case.

Reproductive ageing is closely associated with the quantity and quality of the pool of follicles in the ovaries.

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AMH and fertility preservation

An AMH level can also be very useful for young women who want to postpone childbearing and want to check their fertility. Many women these days are postponing having a baby in order to pursue a career.

If your AHM is low, you might want to re-think your priorities. If it’s normal, then you could decide to postpone childbearing, but do get the test repeated every year. We also offer fertility preservation where you can freeze eggs to use in the future.

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